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Products In Development Voclosporin Publications
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The PROMISE study: a phase 2b multicenter study of voclosporin (ISA247) versus tacrolimus in...
Busque S, et al.  American Journal of Transplantation.  2011; Epub Sep 22 read more ...

Oral voclosporin: a novel calcineuirn inhibitor for treatment of noninfectious uveitis
Roesel M, et al.  Clinical Ophthalmology.  2011;5:1309-13 read more ...

Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247...
Kuglstatter A, et al.  Acta Crystallogr D Biol Crystallogr.  2011;67(2):119-23 read more ...

Novel immunosuppressive agents in kidney transplantation
Cooper JE, et al.  Clinical Nephrology.  2010;73(5):333-43 read more ...

LX211 (voclosporin) suppresses experimental uveitis and inhibits human T cells.
Cunningham MA, et al.  Invest Ophthalmol Vis Sci.  2009;50(1):249-55 read more ...

A new agent for the treatment of noninfectious uveitis: rationale and design of three LUMINATE...
Anglade E, et al.  Clinical Ophthalmology.  2008;2(4):693-702 read more ...

Development and validation of a LC/MS/MS method for quantifying the next generation calcineurin...
Handy R, et al.  J Chromatogr B Analyt Technol Biomed Life Sci.  2008;874(1-2):57-63 read more ...

Efficacy of ISA247 in plaque psoriasis: a randomised, multicenter, double-blind, placebo...
Papp K, et al.  The Lancet.  2008;371(9621):1337-42 read more ...

Next-generation calcineurin inhibitors for ophthalmic indications
Anglade E, et al.  Expert Opin Investig Drugs.  2007;16(10):1525-40 read more ...

A randomized, multicenter, double-blind, placebo-controlled phase 2 trial of ISA247 in patients...
Bissonnette R, et al.  J Am Acad Dermatol.  2006;54(3):472-78 read more ...

The novel calcineurin inhibitor IDSA247: a more potent immunosuppressant than cyclosporin in vitro
Birsan T, et al.  Transpl Int. 2005;17(12):767-71 read more ...

Compared with cyclosporin, ISATX247 significantly prolongs renal-allograft survival in a nonhuman...
Gregory CR, et al.  Transplantation.  2004;78(5):681-85 read more ...

In vivo evaluation of the novel calcineurin inhibitor ISATX247 in non-human primates
Stalder M, et al.  J Heart Lung Transplant.  2003;22(12):1343-52 read more ...

Amelioration of accelerated collagen induced arthritis by a novel calcineurin inhibitor, ISA(TX)247
Maksymowych WP, et al.  J Rheumatol.  2002;29(8):1646-52 read more ...

ISATX247: a novel calcineurin inhibitor
Abel MD, et al.  J Heart Lung Transplant. 2001;20(2):161 read more ...

ISA(TX)247: a novel calcineurin inhibitor
Aspeslet L, et al.  Transplant Proc.  2001;33(1-2):1048-51 read more ...
Abstracts

Isotechnika's Scientific abstracts are available in a consolidated PDF file.

Scientific Abstracts December 2011.pdf
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